Clean Teeth May Reduce Parkinson’s Risk: New Study

Clean Teeth May Reduce Parkinson’s Risk: New Study

Clean Teeth May Reduce Parkinson’s Risk: New Study

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New Study: Keeping This One Body Part Clean Can Reduce Your Parkinson’s Risk Parkinson’s disease, a debilitating neurological disorder that impacts more than 1.1 million people in the U.S., remains a challenging condition for both patients and healthcare professionals. The hallmark symptoms of Parkinson’s, including tremors, stiffness, and slowed movement, can have a significant impact on a person’s quality of life. While the exact cause of Parkinson’s disease remains unclear, emerging research suggests that the gut-brain axis may play a crucial role in its development. A recent study published in Nature Communications in September 2025 sheds new light on a surprising connection between oral health and Parkinson's disease. Researchers from South Korea's Pohang University of Science & Technology found that Streptococcus mutans, a common bacterium known for causing cavities, may contribute to the development of Parkinson’s disease. The study revealed that Streptococcus mutans can travel from the mouth to the gut, where it produces compounds that could potentially damage brain cells involved in movement and coordination. This finding is particularly significant as previous research has shown that individuals with Parkinson’s have higher levels of S. mutans in their gut microbiome compared to healthy individuals. Further analysis of fecal samples from individuals with Parkinson’s revealed that S. mutans can produce an enzyme called imidazole propionate (ImP), which can travel to the brain and lead to the loss of dopamine-producing neurons. This process ultimately contributes to the progression of Parkinson’s disease. In experiments conducted on mice, researchers found that introducing S. mutans or genetically modified E. coli into the guts of the animals led to increased levels of imidazole propionate in the blood and brain. As a result, the mice exhibited key features of Parkinson’s, including the loss of dopamine-producing neurons, increased brain inflammation, motor dysfunction, and accumulation of alpha-synuclein, a protein associated with Parkinson’s progression. Assistant professor of molecular medicine, Ara Koh, a co-author of the study, emphasized the significance of these findings, stating, "Our study provides a mechanistic understanding of how oral microbes in the gut can influence the brain and contribute to the development of Parkinson’s disease. It highlights the potential of targeting the gut microbiota as a therapeutic strategy, offering a new direction for Parkinson’s treatment." In addition to elucidating the role of oral microbes in Parkinson's disease, the researchers discovered that the Parkinson-like effects observed in the mice depended on the activation of a signaling protein complex called mTORC1. When the mice were treated with a medication that inhibited mTORC1, their symptoms improved, suggesting a potential therapeutic avenue for managing Parkinson’s disease. In conclusion, maintaining good oral hygiene and keeping the oral microbiome in balance may play a crucial role in reducing the risk of developing Parkinson’s disease. By understanding the intricate connections between oral health, gut bacteria, and brain health, researchers are paving the way for innovative treatments and interventions for Parkinson’s patients. This groundbreaking study underscores the importance of holistic approaches to disease prevention and management, emphasizing the interconnectedness of various bodily systems. As we continue to unravel the mysteries of Parkinson’s disease, one thing remains clear: taking care of our bodies, both inside and out, is essential for promoting overall health and well-being. In the quest to combat Parkinson’s disease, maintaining a clean and healthy body part may hold the key to a brighter future for millions of individuals living with this challenging condition. Let this study serve as a reminder of the profound impact that simple daily habits, such as practicing good oral hygiene, can have on our long-term health and well-being.
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Hi, I’m Ciro Irmici, an entrepreneur and investor from San Severo, Italy. My passions range from investments (stocks, crypto, dividends) to automation and creating businesses that help people. I believe in building things that matter, like a gym for all and a theatre for people to enjoy music. I love learning and sharing what I learn: how to create eBooks, audiobooks, and other digital products. I’m also deeply into fitness (gym, running, jump rope) and creativity (painting, music, design). My ultimate goal? To reach financial freedom and help others achieve their dreams.

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